Bottom Entry Inline Mixer
In standard hygienic processing workshops, high-shear homogenization and material transfer often require separate pieces of equipment including standalone mixers and independent delivery pumps. Extra piping and auxiliary pumping units increase cross-contamination risks, uneven shear damage to formulations and frequent mechanical seal failures. The BOFRD-1 Series Bottom Entry Inline Mixer solves these pain points with an integrated external circulation layout. Mounted at the tank bottom with built-in recirculation pipelines, this unit delivers continuous circulating shear to refine particle sizes while directly transferring materials to downstream storage vessels. It fits narrow small tanks, production lines with limited overhead installation space, multi-emulsifier parallel layouts and low-volume batch production. Stable operation under vacuum and pressurized environments makes it a viable processing solution for high-cleanliness pharmaceutical, food and cosmetic facilities complying with GMP standards.
Combined Circulating Shearing and Fluid Conveying Mechanics
The core technical advantage of the BOFRD-1 Series lies in its dual functionality of homogenization and material transportation. Installed at the lowest section of process tanks, high-speed rotors draw coarse materials, agglomerated powders and immiscible liquids into the shear chamber under gravity pressure. Materials receive intense hydraulic and mechanical shear while passing through precision-machined stator gaps. The internal chamber structure converts shear kinetic energy into stable fluid pressure ranging from 0.03 MPa to 0.40 MPa. Homogenized materials flow through external recirculation pipelines back to the tank top or directly to subsequent processing tanks, eliminating the need for extra feeding pumps. The continuous circulation loop ensures every fraction of raw materials undergoes repeated high-shear treatment to achieve uniform submicron dispersion.
Optimized Layout for Restricted Cleanroom Space
Many modular cleanrooms reserve the tank dome for vacuum pipelines, CIP spray balls and powder feeding ports. Traditional top-mounted mixers occupy overhead space and cause structural conflicts. The bottom-mounted drive structure of the BOFRD-1 fully frees up the tank top for all essential auxiliary process hardware. Standard top-entry mixing equipment demands sufficient liquid depth to submerge rotor-stator assemblies, which leads to incomplete mixing and raw material waste during small trial batches. The bottom-entry design keeps shear components fully immersed even for minimum feeding volumes and cuts residual product loss significantly. Its bottom flange sealing structure maintains stable tightness during long-term vacuum or pressurized production cycles and prevents oxygen-induced deterioration of sensitive pharmaceutical ingredients.

Sanitary Material Selection and High Temperature Resistance
All fluid contact components adopt premium AISI 304 or AISI 316 stainless steel to avoid metal ion precipitation and raw material contamination. The whole machine features a compact simplified structure for easy disassembly, assembly and manual cleaning. Standard configurations support regular CIP flushing cycles, while customized versions with high-temperature resistant elastomers and electropolished surfaces withstand continuous working temperatures up to 160°C for CIP and SIP sterilization processes. The unit is equipped with globally renowned brand motors for stable low-noise operation and robust long-term service performance. All internal flow paths eliminate stagnant dead zones to prevent material accumulation and microbial growth.
Full Modular Customization Matrix
Diverse formulation characteristics require flexible configurable components, and the BOFRD-1 Series supports fully personalized matching for all core parts.
Motor options cover standard general-purpose motors and ATEX explosion-proof motors for flammable processing zones.
Surface treatment includes mirror electropolishing and sandblasting to meet different sanitary and wear-resistance demands.
Mechanical sealing choices contain single mechanical seals for regular atmospheric production and double mechanical seals for sterile vacuum workshops. Optional friction pair combinations are graphite paired with silicon carbide, graphite paired with tungsten carbide and dual tungsten carbide matching surfaces for abrasive slurry processing.
FDA-compliant elastomer sealing rings include EPDM, high-temperature silicone and chemically inert fluororubber to guarantee compatibility with various APIs and solvent carriers.
Power supply specifications support 380V 50Hz and 380V 60Hz to adapt to factory power systems worldwide.
Customizable technical parameters cover rotor diameter, motor power, operating rotating speed, circulation flow rate and matching tank volume to satisfy unique production throughput requirements.
Reliable Scalability From Lab Pilot to Large-Scale Production
The complete BOFRD-1 product range enables seamless process scaling from small lab batches to industrial mass manufacturing. The compact BOFRD1-60 model adopts a 0.75 kW motor for 20–50 liter pilot tanks with a circulation flow rate of 1 ton per hour. The heavy-duty BOFRD1-380 industrial model uses a 90 kW high-torque drive and delivers a maximum circulation capacity of 120 tons per hour to process batches up to 10,000 liters. All models maintain proportional rotor-stator geometry and rotor tip speed during size iteration. Manufacturers adjust tank volumes without modifying homogenization cycle parameters and retain consistent finished product quality across all production scales.
Share your complete production parameters to acquire a tailored configuration plan for the Bottom Entry Inline Mixer. Key reference information includes raw material viscosity and density, target circulation flow rate, total batch processing duration, special certification requirements such as explosion-proof standards and material traceability documents. Our engineering team can provide custom pipeline layout drawings and calculate accurate discharge pressure values matching your on-site production layout.
Description
In standard hygienic processing workshops, high-shear homogenization and material transfer often require separate pieces of equipment including standalone mixers and independent delivery pumps. Extra piping and auxiliary pumping units increase cross-contamination risks, uneven shear damage to formulations and frequent mechanical seal failures. The BOFRD-1 Series Bottom Entry Inline Mixer solves these pain points with an integrated external circulation layout. Mounted at the tank bottom with built-in recirculation pipelines, this unit delivers continuous circulating shear to refine particle sizes while directly transferring materials to downstream storage vessels. It fits narrow small tanks, production lines with limited overhead installation space, multi-emulsifier parallel layouts and low-volume batch production. Stable operation under vacuum and pressurized environments makes it a viable processing solution for high-cleanliness pharmaceutical, food and cosmetic facilities complying with GMP standards.
Combined Circulating Shearing and Fluid Conveying Mechanics
The core technical advantage of the BOFRD-1 Series lies in its dual functionality of homogenization and material transportation. Installed at the lowest section of process tanks, high-speed rotors draw coarse materials, agglomerated powders and immiscible liquids into the shear chamber under gravity pressure. Materials receive intense hydraulic and mechanical shear while passing through precision-machined stator gaps. The internal chamber structure converts shear kinetic energy into stable fluid pressure ranging from 0.03 MPa to 0.40 MPa. Homogenized materials flow through external recirculation pipelines back to the tank top or directly to subsequent processing tanks, eliminating the need for extra feeding pumps. The continuous circulation loop ensures every fraction of raw materials undergoes repeated high-shear treatment to achieve uniform submicron dispersion.
Optimized Layout for Restricted Cleanroom Space
Many modular cleanrooms reserve the tank dome for vacuum pipelines, CIP spray balls and powder feeding ports. Traditional top-mounted mixers occupy overhead space and cause structural conflicts. The bottom-mounted drive structure of the BOFRD-1 fully frees up the tank top for all essential auxiliary process hardware. Standard top-entry mixing equipment demands sufficient liquid depth to submerge rotor-stator assemblies, which leads to incomplete mixing and raw material waste during small trial batches. The bottom-entry design keeps shear components fully immersed even for minimum feeding volumes and cuts residual product loss significantly. Its bottom flange sealing structure maintains stable tightness during long-term vacuum or pressurized production cycles and prevents oxygen-induced deterioration of sensitive pharmaceutical ingredients.

Sanitary Material Selection and High Temperature Resistance
All fluid contact components adopt premium AISI 304 or AISI 316 stainless steel to avoid metal ion precipitation and raw material contamination. The whole machine features a compact simplified structure for easy disassembly, assembly and manual cleaning. Standard configurations support regular CIP flushing cycles, while customized versions with high-temperature resistant elastomers and electropolished surfaces withstand continuous working temperatures up to 160°C for CIP and SIP sterilization processes. The unit is equipped with globally renowned brand motors for stable low-noise operation and robust long-term service performance. All internal flow paths eliminate stagnant dead zones to prevent material accumulation and microbial growth.
Full Modular Customization Matrix
Diverse formulation characteristics require flexible configurable components, and the BOFRD-1 Series supports fully personalized matching for all core parts.
Motor options cover standard general-purpose motors and ATEX explosion-proof motors for flammable processing zones.
Surface treatment includes mirror electropolishing and sandblasting to meet different sanitary and wear-resistance demands.
Mechanical sealing choices contain single mechanical seals for regular atmospheric production and double mechanical seals for sterile vacuum workshops. Optional friction pair combinations are graphite paired with silicon carbide, graphite paired with tungsten carbide and dual tungsten carbide matching surfaces for abrasive slurry processing.
FDA-compliant elastomer sealing rings include EPDM, high-temperature silicone and chemically inert fluororubber to guarantee compatibility with various APIs and solvent carriers.
Power supply specifications support 380V 50Hz and 380V 60Hz to adapt to factory power systems worldwide.
Customizable technical parameters cover rotor diameter, motor power, operating rotating speed, circulation flow rate and matching tank volume to satisfy unique production throughput requirements.
Reliable Scalability From Lab Pilot to Large-Scale Production
The complete BOFRD-1 product range enables seamless process scaling from small lab batches to industrial mass manufacturing. The compact BOFRD1-60 model adopts a 0.75 kW motor for 20–50 liter pilot tanks with a circulation flow rate of 1 ton per hour. The heavy-duty BOFRD1-380 industrial model uses a 90 kW high-torque drive and delivers a maximum circulation capacity of 120 tons per hour to process batches up to 10,000 liters. All models maintain proportional rotor-stator geometry and rotor tip speed during size iteration. Manufacturers adjust tank volumes without modifying homogenization cycle parameters and retain consistent finished product quality across all production scales.
Share your complete production parameters to acquire a tailored configuration plan for the Bottom Entry Inline Mixer. Key reference information includes raw material viscosity and density, target circulation flow rate, total batch processing duration, special certification requirements such as explosion-proof standards and material traceability documents. Our engineering team can provide custom pipeline layout drawings and calculate accurate discharge pressure values matching your on-site production layout.
Application






Specifications
| Model | BOFRD1-60 | BOFRD1-90 | BOFRD1-100 | BOFRD1-110 | BOFRD1-120 | BOFRD1-140 | BOFRD1-165 | BOFRD1-185 | BOFRD1-200 | BOFRD1-260 | BOFRD1-320 | BOFRD1-350 | BOFRD1-380 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Power | 0.75 | 1.5 | 2.2 | 3 | 4 | 5.5 | 7.5 | 11 | 15 | 22 | 37 | 55 | 90 | kw |
| Capacity | 20-50 | 50-100 | 80-200 | 100-250 | 150-300 | 200-400 | 300-500 | 500-1000 | 800-1500 | 1000-2000 | 1500-3000 | 2000-5000 | 3000-10000 | L |
| Speed | 2800-2900 | 2800-2900 | 2800-2900 | 2800-2900 | 2800-2900 | 2800-2900 | 2800-2900 | 2800-2900 | 2800-2900 | 1470 | 1470 | 1470 | 1470 | rmp |
| Outlet Pressure | 0.03 | 0.04 | 0.05 | 0.06 | 0.07 | 0.08 | 0.10 | 0.15 | 0.20 | 0.20 | 0.30 | 0.35 | 0.40 | mpa |
| Outlet Size2 | 20 | 25 | 32 | 32 | 40 | 40 | 40 | 50 | 65 | 80 | 100 | 125 | 150 | mm |
| Circulation Flow Rate | 1 | 2 | 3 | 4 | 5 | 7 | 10 | 15 | 20 | 40 | 50 | 80 | 120 | t/h |
Advantage Comparison













